In the least surprising news of the day Womens Marquise Goodwin Jersey , the San Francisco 49ers odds to win Super Bowl 53 have taken a sizable hit. Entering Week 3, the 49ers were anywhere from 25/1 to 35/1, depending on your sportsbook of choice. Following the loss and Jimmy Garoppolo’s torn ACL, the odds have dipped considerably.A few sportsbooks monitored by OddsShark have not updated their Super Bowl 53 odds, but the ones that have all dropped them to at least 80/1. Additionally, SportBet www.the49ersfootballauthentic.com , 5Dimes, and the Westgate SuperBook all have moved the 49ers to 500/1. Different sportsbooks look at futures odds differently, and some have different scales for measuring out the long shots. Either way, they’re hoping to draw in a few sucker bets on the 49ers to make some easy cash.Meanwhile, the spread for this weekend’s 49ers-Chargers matchup is growing. It opened at 9.5, and quickly climbed to 10.5 at most sportsbooks. It has now risen to 11.5 at 5Dimes and SportBet San Francisco 49ers T-Shirt , and money continues to pour in on the Chargers.The 49ers are going to struggle as the season moves along, but I would not be surprised to see some sharp money come in on them now that the line is north of 11. They say you should bet the number not the team. I’d say stay the heck away from the 49ers for the time being, but for some of these matchups, there could be some value in a contrarian bet. The Chargers are not one of the worst teams in the league, but they have a ton of question marks. The 49ers defense struggled against Kansas City, but a bounce-back effort could turn this into a competitive game on Sunday.I don’t know that I have the stones to take the 49ers as double digit dogs with one of my five SuperContest picks San Francisco 49ers Hats , but it’s at least intriguing as the line climbs higher.Golden Nuggets: Too. Many. Injuries The one thing growing aggravating about the San Francisco 49ers is the injuries. Too. Many. Injuries. This team has clearly been snakebit on the injury front with them just trying to find bodies to get them through the weekend. This is a blessing in disguise for the younger players, as it gets them some playing time, but it still hurts productivity. It has me wondering what the deal is. Is this a conditioning problem? A style problem? Or just bad luck for the snake? I’m going with the latter. This just happens. The 49ers have had years where they were very fortunate to dodge massive injuries. This season is not one of them. The amount they are getting though certainly is a bit concerning isn’t it? What do you think?While you think about it, here’s some links: Kyle Shanahan’s dual roles not helping 49ers (Cohn)49ers RB Matt Breida needs more touches in run game (Madson)Film Review: How third-down struggles have plagued 49ers defense (KNBR)49ers mailbag: Do Lynch and Co. have a problem evaluating talent? (Biderman)D.J. Reed making push for starting free safety job (Madson)Kyle Shanahan explains how Chargers’ mistake clinched win (Maiocco)Best and worst QBs of Week 4: Trubisky jumps from worst to first (ESPN)49ers dodge bullet with Joe Staley’s knee, but injuries still loom large (Biderman)Kyle Shanahan explains decision to stray away from the run in Week 4 loss (KNBR)What a horrible night to have a curse...